Anti-Cytokeratin 20 抗体 [BV12], prediluted (ab73096)

製品の概要

  • 製品名Anti-Cytokeratin 20 antibody [BV12], prediluted
    Cytokeratin 20 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [BV12] to Cytokeratin 20, prediluted
  • アプリケーション適用あり: IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide from the C-terminus of human Cytokeratin 20 protein.

  • ポジティブ・コントロール
    • Colon carcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab73096 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
IHC-Fr
  • 追加情報IHC-P: Use neat for 30-60 minutes at room temperature.
    Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 1 mM EDTA buffer, pH 8.0 prior to immunostaining.
    IHC-Fr (acetone-fixed): Use neat for 30-60 minutes at room temperature.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine.
    • 組織特異性Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
    • 配列類似性Belongs to the intermediate filament family.
    • 発生段階First detected at embryonic week 8 in individual 'converted' simple epithelial cells of the developing intestinal mucosa. In later fetal stages, synthesis extends over most goblet cells and a variable number of villus enterocytes. In the developing gastric and intestinal mucosa, expressed in all enterocytes and goblet cells as well as certain 'low-differentiated' columnar cells, whereas the neuroendocrine and Paneth cells are negative.
    • 翻訳後修飾Hyperphosphorylation at Ser-13 occurs during the early stages of apoptosis but becomes less prominent during the later stages. Phosphorylation at Ser-13 also increases in response to stress brought on by cell injury.
      Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD20 antibody
      • CK 20 antibody
      • CK-20 antibody
      • CK20 antibody
      • Cytokeratin-20 antibody
      • Cytokeratin20 antibody
      • K1C20_HUMAN antibody
      • K20 antibody
      • KA20 antibody
      • Keratin 20 antibody
      • keratin 20, type I antibody
      • keratin 21, rat, homolog of antibody
      • Keratin antibody
      • Keratin type I cytoskeletal 20 antibody
      • Keratin-20 antibody
      • Keratin20 antibody
      • KRT 20 antibody
      • KRT 21 antibody
      • KRT20 antibody
      • KRT21 antibody
      • MGC35423 antibody
      • OTTHUMP00000164518 antibody
      • Protein IT antibody
      • type I cytoskeletal 20 antibody
      see all

    Anti-Cytokeratin 20 antibody [BV12], prediluted 画像

    • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human colon carcinoma tissue, staining Cytokeratin 20 with ab73096.

    Anti-Cytokeratin 20 antibody [BV12], prediluted (ab73096) 使用論文

    ab73096 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab73096.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"