Anti-Cytokeratin 19 抗体 [RCK108], prediluted (ab49912)

製品の概要

  • 製品名Anti-Cytokeratin 19 antibody [RCK108], prediluted
    Cytokeratin 19 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [RCK108] to Cytokeratin 19, prediluted
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Tissue/ cell preparation (Human), Cell line T24

  • ポジティブ・コントロール
    • Glandular epithelia
  • 特記事項


    This antibody stains practically all epithelial tumours, especially adenocarcinoma. Staining is negative in hepatocellular carcinoma and also in most medullary and weakly differentiated ductal carcinomas.

製品の特性

  • 製品の状態Prediluted
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: Phosphate buffer, pH 7.3
  • Concentration information loading...
  • 精製度Tissue culture supernatant
  • 一次抗体 備考This antibody stains practically all epithelial tumours, especially adenocarcinoma. Staining is negative in hepatocellular carcinoma and also in most medullary and weakly differentiated ductal carcinomas.
  • ポリ/モノモノクローナル
  • クローン名RCK108
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab49912 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Use Neat, 100µl per test.

WB Use at an assay dependent concentration. Detects a band of approximately 40 kDa (predicted molecular weight: 48 kDa).

ターゲット情報

  • 機能Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
  • 組織特異性Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
  • 配列類似性Belongs to the intermediate filament family.
  • 発生段階Present in hair follicles at all stages of development.
  • ドメインThis keratin differs from all other IF proteins in lacking the C-terminal tail domain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 40 kDa keratin intermediate filament antibody
    • CK 19 antibody
    • CK-19 antibody
    • CK19 antibody
    • Cytokeratin 19 antibody
    • Cytokeratin-19 antibody
    • K19 antibody
    • K1C19_HUMAN antibody
    • K1CS antibody
    • Keratin 19 antibody
    • Keratin type I 40 kD antibody
    • Keratin type I 40kD antibody
    • Keratin type I cytoskeletal 19 antibody
    • Keratin, type I cytoskeletal 19 antibody
    • Keratin, type I, 40 kd antibody
    • Keratin-19 antibody
    • KRT19 antibody
    • MGC15366 antibody
    see all

Anti-Cytokeratin 19 antibody [RCK108], prediluted (ab49912) 使用論文

ab49912 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"