Anti-Cytokeratin 13 抗体 (ab97327)
Key features and details
- Rabbit polyclonal to Cytokeratin 13
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-Cytokeratin 13 antibody
Cytokeratin 13 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Cytokeratin 13 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse -
免疫原
Recombinant fragment corresponding to a region within amino acids 198-448 of Human Cytokeratin 13 (NP_705694).
-
ポジティブ・コントロール
- WB: HeLa whole cell lysate ICC/IF: A431 cells
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab97327の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 50 kDa.
|
|
ICC/IF |
1/100 - 1/200.
|
特記事項 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 50 kDa. |
ICC/IF
1/100 - 1/200. |
ターゲット情報
-
組織特異性
Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta. -
関連疾患
Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved. -
配列類似性
Belongs to the intermediate filament family. -
翻訳後修飾
O-glycosylated; glycans consist of single N-acetylglucosamine residues. - Information by UniProt
-
参照データベース
- Entrez Gene: 3860 Human
- Entrez Gene: 16663 Mouse
- Omim: 148065 Human
- SwissProt: P13646 Human
- SwissProt: P08730 Mouse
- Unigene: 654550 Human
- Unigene: 4646 Mouse
-
別名
- 47 kDa cytokeratin antibody
- CK-13 antibody
- CK13 antibody
see all
画像
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (2)
ab97327 は 2 報の論文で使用されています。
- Lungova V et al. Exposure to e-cigarette vapor extract induces vocal fold epithelial injury and triggers intense mucosal remodeling. Dis Model Mech 15:N/A (2022). PubMed: 35770504
- Imaizumi M et al. In vitro epithelial differentiation of human induced pluripotent stem cells for vocal fold tissue engineering. Ann Otol Rhinol Laryngol 122:737-47 (2013). PubMed: 24592576