Anti-Cytokeratin 10 抗体 [DE-K10] (ab80523)


  • 製品名Anti-Cytokeratin 10 antibody [DE-K10]
    Cytokeratin 10 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [DE-K10] to Cytokeratin 10
  • アプリケーション適用あり: WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Rat, Cat, Dog, Human
  • 免疫原

    Cytoskeletal preparation extracted from Human ectocervical epithelium.

  • ポジティブ・コントロール
    • A431 cells. Skin.


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 10mM PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名DE-K10
  • アイソタイプIgG1
  • 研究分野


Our Abpromise guarantee covers the use of ab80523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報ICC/IF: Use at an assay dependent dilution.
    IHC-P: Use at a concentration of 0.5 - 1 µg/ml. Antigen retrieval is not required.
    WB: Use at a concentration of 1 - 2 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 60 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 組織特異性Seen in all suprabasal cell layers including stratum corneum.
    • 関連疾患Defects in KRT10 are a cause of bullous congenital ichthyosiform erythroderma (BCIE) [MIM:113800]; also known as epidermolytic hyperkeratosis (EHK) or bullous erythroderma ichthyosiformis congenita of Brocq. BCIE is an autosomal dominant skin disorder characterized by widespread blistering and an ichthyotic erythroderma at birth that persist into adulthood. Histologically there is a diffuse epidermolytic degeneration in the lower spinous layer of the epidermis. Within a few weeks from birth, erythroderma and blister formation diminish and hyperkeratoses develop.
      Defects in KRT10 are a cause of ichthyosis annular epidermolytic (AEI) [MIM:607602]; also known as cyclic ichthyosis with epidermolytic hyperkeratosis. AEI is a skin disorder resembling bullous congenital ichthyosiform erythroderma. Affected individuals present with bullous ichthyosis in early childhood and hyperkeratotic lichenified plaques in the flexural areas and extensor surfaces at later ages. The feature that distinguishes AEI from BCIE is dramatic episodes of flares of annular polycyclic plaques with scale, which coalesce to involve most of the body surface and can persist for several weeks or even months.
    • 配列類似性Belongs to the intermediate filament family.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BCIE antibody
      • BIE antibody
      • CK 10 antibody
      • CK-10 antibody
      • Cytokeratin-10 antibody
      • EHK antibody
      • K10 antibody
      • K1C10_HUMAN antibody
      • Keratin 10 antibody
      • Keratin antibody
      • Keratin type i cytoskeletal 10 antibody
      • Keratin type I cytoskeletal 59 kDa antibody
      • Keratin-10 antibody
      • Keratin10 antibody
      • KPP antibody
      • KRT10 antibody
      • type I cytoskeletal 10 antibody
      see all

    Anti-Cytokeratin 10 antibody [DE-K10] 画像

    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human skin tissue using 1µg/ml ab80519 in with a peroxidase-conjugated secondary antibody and an AEC chromogen. Note cytoplasmic staining of epidermal region.
    • Anti-Cytokeratin 10 antibody [DE-K10] (ab80523) at 2 µg/ml + A431 cell lysate

      Predicted band size : 60 kDa
      Observed band size : 60 kDa

    Anti-Cytokeratin 10 antibody [DE-K10] (ab80523) 使用論文

    ab80523 has not yet been referenced specifically in any publications.

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