Anti-Cytochrome P450 Reductase 抗体 (ab106255)

製品の概要

  • 製品名Anti-Cytochrome P450 Reductase antibody
    Cytochrome P450 Reductase 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Cytochrome P450 Reductase
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
    交差が予測される動物種: Rabbit, Guinea pig, Cow, Dog, Pig, Xenopus laevis, Chinese Hamster
  • 免疫原

    Synthetic peptide:

    C-TNPPRTNVLYE

    , corresponding to internal sequence amino acids 381-391 of Human Cytochrome P450 Reductase (NP_000932.3).

  • ポジティブ・コントロール
    • Human, Mouse and Rat Liver lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106255 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 77 kDa).

ターゲット情報

  • 機能This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
  • 関連疾患Defects in POR are the cause of adrenal hyperplasia variant type (AHV) [MIM:201750]; also known as Antley-Bixler syndrome-like phenotype with disordered steroidogenesis. AHV is a rare variant of congenital adrenal hyperplasia. It is an autosomal recessive disorder with apparent combined P450C17 and P450C21 deficiency. Affected girls are born with ambiguous genitalia, but their circulating androgens are low and virilization does not progress. Conversely, affected boys are sometimes born undermasculinized. Boys and girls can also present with bone malformations, in some cases resembling the pattern seen in patients with Antley-Bixler syndrome.
    Defects in POR are a cause of isolated disordered steroidogenesis (IDS) [MIM:201750].
  • 配列類似性In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
    Contains 1 FAD-binding FR-type domain.
    Contains 1 flavodoxin-like domain.
  • 細胞内局在Endoplasmic reticulum membrane. Anchored to the ER membrane by its N-terminal hydrophobic region.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CPR antibody
    • CYPOR antibody
    • DKFZp686G04235 antibody
    • FLJ26468 antibody
    • NADPH Cytochrome P450 Reductase antibody
    • NADPH dependent cytochrome P450 reductase antibody
    • NADPH--cytochrome P450 reductase antibody
    • NCPR_HUMAN antibody
    • P450 (cytochrome) oxidoreductase antibody
    • P450 Cytochrome Oxidoreductase antibody
    • P450R antibody
    • por antibody
    see all

Anti-Cytochrome P450 Reductase antibody 画像

  • Anti-Cytochrome P450 Reductase antibody (ab106255) at 0.1 µg/ml + Rat Liver lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 77 kDa

Anti-Cytochrome P450 Reductase antibody (ab106255) 使用論文

ab106255 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"