Anti-Cytochrome P450 2D4 抗体 (ab22592)

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製品の概要

  • 製品名
    Anti-Cytochrome P450 2D4 antibody
  • 製品の詳細
    Rabbit polyclonal to Cytochrome P450 2D4
  • 由来種
    Rabbit
  • 特異性
    ab22592 recognises Cytochrome P450 2D4
  • アプリケーション
    適用あり: WB, IHC-Fr, IHC-Pmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Synthetic pentapeptide which corresponding to the C terminal of rat liver Cytochrome P450 2D4 which was conjugated to keyhole limpet haemocyanin using a maleimido linkage.

  • ポジティブ･コントロール
    • clozapine treated rat brain preparations
  • 特記事項
    ab22592 is not suitable for human studies.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab22592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 57 kDa.
IHC-Fr 1/1000. Using ABC Elite detection.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 関連性
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  • 細胞内局在
    Endoplasmic reticulum
  • 参照データベース
    • 別名
      • Cyp2d18 antibody
      • Cyp2d4 antibody
      • Cyp2d4v1 antibody
      • CYPIID18 antibody
      • Cytochrome P450 2d18 antibody
      • Cytochrome P450 subfamily IID4 antibody
      see all

    参考文献

    ab22592 has not yet been referenced specifically in any publications.

    ab22592 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    レビューと Q&A

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    2 reviews or Q&A

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    Thank you very much for your kind answer. I think that ABCAM would be interested in the check how these antibodies working in new kind of test ( immunoinhibition). With pleasure we would throw open results of our research with the use of IgG anti-CYP2...

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    I understand your situation. Antibodies are expensive and committing funds to an experiment that may or may not work is a difficult decision. However, we do not have free samples or discounts for the application you want to test, immuno-inhibition. ...

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    We would like to demonstrate that the O-demethylation of 5-methoxytryptamine (5MT) to serotonin is catalyzed by the enzyme CYP2D4 in rat brain microsomes. Therefore anti-CYP2D4 antibodies (ab22592) were added to the reaction mixture consist...

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    Thank you for your description of your experiment and results. This is the first report we have received of a neutralization assay with these antibodies; they have only been tested in detection assays such as IHC and western blotting or, in the case of...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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