Anti-CYP2A6 抗体 [F16 P2 D8] (ab56069)
Key features and details
- Mouse monoclonal [F16 P2 D8] to CYP2A6
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-CYP2A6 antibody [F16 P2 D8]
CYP2A6 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [F16 P2 D8] to CYP2A6 -
由来種
Mouse -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human CYP2A6 (C terminal) conjugated to ovalbumin.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
F16 P2 D8 -
ミエローマ
Ag8.653 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab56069の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 57 kDa).
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IHC-P |
Use a concentration of 1 µg/ml.
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 57 kDa). |
IHC-P
Use a concentration of 1 µg/ml. |
ターゲット情報
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機能
Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity. -
組織特異性
Liver. -
配列類似性
Belongs to the cytochrome P450 family. -
細胞内局在
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1548 Human
- Omim: 122720 Human
- SwissProt: P11509 Human
- Unigene: 250615 Human
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別名
- Coumarin 7 hydroxylase antibody
- Coumarin 7-hydroxylase antibody
- CP2A6_HUMAN antibody
see all
画像
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Anti-CYP2A6 antibody [F16 P2 D8] (ab56069) at 1 µg/ml + Recombinant cytochrome p450
Predicted band size: 57 kDa
Observed band size: 54 kDa why is the actual band size different from the predicted? -
This image shows normal human liver tissue stained by ab56069 at 1µg/ml.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab56069 は 1 報の論文で使用されています。
- Dhamankar V et al. Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa. Inhal Toxicol 27:767-77 (2015). PubMed: 26572092