The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報ELISA: Use at an assay dependent dilution.
WB: 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 15 kDa).
This antibody has only been tested against the recombinant fragment, and not the endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
関連疾患Defects in CYB5A are the cause of methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:250790]. A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia.
配列類似性Belongs to the cytochrome b5 family. Contains 1 cytochrome b5 heme-binding domain.
細胞内局在Cytoplasm and Endoplasmic reticulum membrane. Microsome membrane.