Cytochalasin D, actin polymerization inhibitor (ab143484)
Key features and details
- Potent actin polymerization inhibitor
- CAS Number: 22144-77-0
- Purity: > 98%
- Soluble in ethanol to 10 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Zygosporium mansonii
製品の概要
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製品名
Cytochalasin D, actin polymerization inhibitor -
製品の詳細
Potent actin polymerization inhibitor -
精製度
> 98% -
CAS 番号
22144-77-0 -
構造式
製品の特性
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体系名
(3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(Acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6-12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1,11(2H)-dione -
分子量
507.63 -
分子式
C30H37NO6 -
PubChem 登録番号
5458428 -
保存方法
Shipped at 4°C. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in ethanol to 10 mM and in DMSO to 50 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)O -
由来
Zygosporium mansonii
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (15)
ab143484 は 15 報の論文で使用されています。
- Ran J et al. Targeting the HDAC6-Cilium Axis Ameliorates the Pathological Changes Associated with Retinopathy of Prematurity. Adv Sci (Weinh) 9:e2105365 (2022). PubMed: 35619548
- Kim HS et al. Förster Resonance Energy Transfer-Based Single-Cell Imaging Reveals Piezo1-Induced Ca2+ Flux Mediates Membrane Ruffling and Cell Survival. Front Cell Dev Biol 10:865056 (2022). PubMed: 35646889
- Cui Z et al. Altered pain sensitivity in 5×familial Alzheimer disease mice is associated with dendritic spine loss in anterior cingulate cortex pyramidal neurons. Pain 163:2138-2153 (2022). PubMed: 35384934
- Zhao Y et al. Focal adhesion regulates osteogenic differentiation of mesenchymal stem cells and osteoblasts. Biomater Transl 2:312-322 (2021). PubMed: 35837413
- Starostina I et al. Distinct calcium regulation of TRPM7 mechanosensitive channels at plasma membrane microdomains visualized by FRET-based single cell imaging. Sci Rep 11:17893 (2021). PubMed: 34504177