製品の概要

  • 製品名Anti-CYP4V2 antibody
    CYP4V2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CYP4V2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide from a region within internal sequence amino acids 432-481 (YFPNPEEFQP ERFFPENAQG RHPYAYVPFS AGPRNCIGQK FAVMEEKTIL) of Human CYP4V2 (NP_997235)

  • ポジティブ・コントロール
    • Jurkat cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab90271 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 61 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12). May have a role in fatty acid and steroid metabolism in the eye.
  • 組織特異性Broadly expressed. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, retina, retinal pigment epithelium (RPE) and lymphocytes.
  • 関連疾患Bietti crystalline corneoretinal dystrophy (BCD) [MIM:210370]: An autosomal recessive ocular disease characterized by retinal degeneration and marginal corneal dystrophy. Typical features include multiple glistening intraretinal crystals scattered over the fundus, a characteristic degeneration of the retina, and sclerosis of the choroidal vessels, ultimately resulting in progressive night blindness and constriction of the visual field. Most patients have similar crystals at the corneoscleral limbus. Patients develop decreased vision, nyctalopia, and paracentral scotomata between the 2nd and 4th decade of life. Later, they develop peripheral visual field loss and marked visual impairment, usually progressing to legal blindness by the 5th or 6th decade of life. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 配列類似性Belongs to the cytochrome P450 family.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BCD antibody
    • CP4V2_HUMAN antibody
    • CYP4AH1 antibody
    • CYP4V 2 antibody
    • CYP4V2 antibody
    • Cytochrome P450 4V2 antibody
    • Cytochrome P450, family 4, subfamily V, polypeptide 2 antibody
    • Retina CYP4V2 antibody
    see all

Anti-CYP4V2 antibody 画像

  • Anti-CYP4V2 antibody (ab90271) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 61 kDa
    Observed band size : 61 kDa
    Additional bands at : 40 kDa. We are unsure as to the identity of these extra bands.

Anti-CYP4V2 antibody (ab90271) 使用論文

ab90271 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab90271.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"