製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Cyclin T2
  • アプリケーション
    適用あり: WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment corresponding to a region within amino acids 497 and 707 of Human Cyclin T2 (NP_490595).

  • ポジティブ・コントロール
    • WB: 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates ICC/IF: Hela cell IHC-P: H1299 Xenograft

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96133 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 81 kDa.
IHC-P 1/100 - 1/250.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能
    Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
  • 組織特異性
    Ubiquitously expressed.
  • 配列類似性
    Belongs to the cyclin family. Cyclin C subfamily.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CCNT2 antibody
    • CCNT2_HUMAN antibody
    • Cyclin T2a antibody
    • Cyclin T2b antibody
    • Cyclin-T2 antibody
    • CycT2 antibody
    • FLJ90560 antibody
    • MGC134840 antibody
    • SDS stable vimentin bound DNA fragment HEF42VIM22 antibody
    • Subunit of positive elongation transcription factor b antibody
    see all

画像

  • Anti-Cyclin T2 antibody (ab96133) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 81 kDa
  • ab96133, at a 1/200 dilution, staining Cyclin T2 in paraformaldehyde fixed A431 cells by Immunofluorescence.
    Lower image: merged with DNA probe.
  • ab96133, at a 1/100 dilution, staining Cyclin T2 in paraffin embedded H1299 xenograft by Immunohistochemistry.

参考文献

This product has been referenced in:
  • Oqani RK  et al. P-TEFb Kinase Activity Is Essential for Global Transcription, Resumption of Meiosis and Embryonic Genome Activation in Pig. PLoS One 11:e0152254 (2016). Read more (PubMed: 27011207) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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