製品の概要

  • 製品名Anti-Cyclin T2 antibody [2128C1a]
    Cyclin T2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2128C1a] to Cyclin T2
  • アプリケーション適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment designed around the C-terminal end of human Cyclin T2.

  • エピトープab50979 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
  • 特記事項This antibody recognizes Cyclin T2a and T2b since it is made by immunogen-peptide that is common domain from both protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, 8.0mM Sodium phosphate, 3mM Potassium chloride, 140mM Sodium chloride, 1.5mM Potassium phosphate, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名2128C1a
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab50979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 81 kDa.
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
  • 組織特異性Ubiquitously expressed.
  • 配列類似性Belongs to the cyclin family. Cyclin C subfamily.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CCNT2 antibody
    • CCNT2_HUMAN antibody
    • Cyclin T2a antibody
    • Cyclin T2b antibody
    • Cyclin-T2 antibody
    • CycT2 antibody
    • FLJ90560 antibody
    • MGC134840 antibody
    • SDS stable vimentin bound DNA fragment HEF42VIM22 antibody
    • Subunit of positive elongation transcription factor b antibody
    see all

Anti-Cyclin T2 antibody [2128C1a] 画像

  • Anti-Cyclin T2 antibody [2128C1a] (ab50979) + recombinant protein fragment used as immunogen.
    Diagram underneath blot depicts region of Cyclin T2 protein that was employed as immunogen (arrow).

    Predicted band size : 81 kDa
  • All lanes : Anti-Cyclin T2 antibody [2128C1a] (ab50979)

    Lane 1 : Molecular Weight Marker
    Lane 2 : 50µg Hela Whole cell lysate
    Lane 3 : 50µg HT-1080 Whole cell lysate
    Lane 4 : 50 µg HEK293 Whole cell lysate
    Lane 5 : 50µg A2058 Whole cell lysate
    Lane 6 : 50µg HIH3T3 Whole cell Lysate

    Secondary
    Lanes 2 - 6 : Mouse IgG Antibody 1/2500

    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 81 kDa


    Exposure time : 1 minute

Anti-Cyclin T2 antibody [2128C1a] (ab50979) 使用論文

This product has been referenced in:
  • Zhang H  et al. SIRT2 directs the replication stress response through CDK9 deacetylation. Proc Natl Acad Sci U S A 110:13546-51 (2013). Read more (PubMed: 23898190) »
  • Wang XS  et al. MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia. Blood 119:4992-5004 (2012). WB ; Human . Read more (PubMed: 22493297) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab50979.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"