Anti-Cyclin H/p34 抗体 [EPR3928] (ab111933)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3928] to Cyclin H/p34
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
-
製品名
Anti-Cyclin H/p34 antibody [EPR3928]
Cyclin H/p34 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR3928] to Cyclin H/p34 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
ポジティブ・コントロール
- Jurkat, A431, K562 and HeLa cell lysates.
-
特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR3928 -
アイソタイプ
IgG -
研究分野
関連製品
-
Alternative Versions
-
Isotype control
-
Positive Controls
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab111933の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/1000 - 1/10000. Predicted molecular weight: 38 kDa.
|
特記事項 |
---|
WB
1/1000 - 1/10000. Predicted molecular weight: 38 kDa. |
ターゲット情報
-
機能
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle. -
配列類似性
Belongs to the cyclin family. Cyclin C subfamily. -
細胞内局在
Nucleus. - Information by UniProt
-
参照データベース
- Entrez Gene: 902 Human
- Entrez Gene: 66671 Mouse
- Entrez Gene: 84389 Rat
- Omim: 601953 Human
- SwissProt: P51946 Human
- SwissProt: Q61458 Mouse
- SwissProt: Q9R1A0 Rat
- Unigene: 292524 Human
see all -
別名
- 6330408H09Rik antibody
- AI661354 antibody
- AV102684 antibody
see all
画像
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab111933 は論文での使用が確認できていません。