製品の概要

  • 製品名Anti-Cyclin H antibody
    Cyclin H 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to Cyclin H
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein corresponding to Human Cyclin H aa 1-323.

  • ポジティブ・コントロール
    • human kidney lysate, transfected 293T cell line, HeLa cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89257 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 37.6 kDa.
ICC/IF Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
  • 配列類似性Belongs to the cyclin family. Cyclin C subfamily.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 6330408H09Rik antibody
    • AI661354 antibody
    • AV102684 antibody
    • AW538719 antibody
    • CAK antibody
    • CAK complex subunit antibody
    • ccnh antibody
    • CCNH_HUMAN antibody
    • CDK activating kinase antibody
    • CDK activating kinase complex subunit antibody
    • Cyclin dependent kinase activating kinase antibody
    • cyclin dependent kinase activating kinase complex subunit antibody
    • Cyclin H antibody
    • Cyclin-H antibody
    • CyclinH antibody
    • MO15 associated protein antibody
    • MO15-associated protein antibody
    • p34 antibody
    • p36 antibody
    • p37 antibody
    see all

Anti-Cyclin H antibody 画像

  • Anti-Cyclin H antibody (ab89257) at 5 µg/ml + human kidney lysate at 50 µg

    Secondary
    HRP goat anti mouse IgG at 1/2500 dilution

    Predicted band size : 37.6 kDa
  • All lanes : Anti-Cyclin H antibody (ab89257) at 5 µg/ml

    Lane 1 : transfected 293T cell line
    Lane 2 : non transfected 293T cell line

    Lysates/proteins at 25 µg per lane.

    Secondary
    HRP goat anti mouse IgG at 1/2500 dilution

    Predicted band size : 37.6 kDa
  • Immunofluorescence analysis of CCR1 expression in HeLa cells using ab89257 at 10 ug/ml

Anti-Cyclin H antibody (ab89257) 使用論文

ab89257 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"