製品の概要

  • 製品名
    Anti-Cyclin G antibody [11C8]
    Cyclin G 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [11C8] to Cyclin G
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment:Prokaryotic recombinant protein corresponding to 142 amino acids of the C terminal region of (human) cyclin G1.

  • ポジティブ・コントロール
    • Immunohistochemistry: Tonsil. Western Blotting: MCF7 cell line.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab49274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報
    IHC-P: 1/20 - 1/40. High temperature antigen unmasking technique. 60 minutes primary antibody incubation at 25oC and standard ABC technique are recommended.
    WB: 1/100 - 1/250. Predicted molecular weight: 34 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
    • 組織特異性
      High levels in skeletal muscle, ovary, kidney and colon.
    • 配列類似性
      Belongs to the cyclin family. Cyclin G subfamily.
    • 発生段階
      Very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells consistent high levels are found throughout the cell cycle.
    • 細胞内局在
      Nucleus. DNA replication foci after DNA damage.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CCNG 1 antibody
      • CCNG antibody
      • CCNG1 antibody
      • CCNG1_HUMAN antibody
      • CYCG1 antibody
      • Cyclin G antibody
      • Cyclin G1 antibody
      • Cyclin-G antibody
      • Cyclin-G1 antibody
      see all

    参考文献

    ab49274 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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