Anti-Cyclin E2 (phospho T392) 抗体 (ab111369)

製品の概要

  • 製品名Anti-Cyclin E2 (phospho T392) antibody
    Cyclin E2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Cyclin E2 (phospho T392)
  • 特異性ab111369 Detects endogenous levels of Cyclin E2 only when phosphorylated at threonine 392.
  • アプリケーション適用あり: ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic phosphopeptide derived from Human Cyclin E2 around the phosphorylation site of threonine 392 (I-M-TP-P-P)

  • ポジティブ・コントロール
    • NIH3T3 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111369 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/100 - 1/500.

ターゲット情報

  • 関連性The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Unlike Cyclin E1, which is expressed in great majority of proliferating normal and neoplastically transformed cells, Cyclin E2 levels are low to undetectable in non transformed cells and increase significantly in neoplasm derived cells.
  • 細胞内局在Nuclear
  • 参照データベース
  • 別名
    • CCN E2 antibody
    • CCNE 2 antibody
    • CCNE2 antibody
    • CCNE2 protein antibody
    • CYC E2 antibody
    • CYCE 2 antibody
    • CYCE2 antibody
    • CyclinE2 antibody
    • G1/S specific cyclin E2 antibody
    see all

Anti-Cyclin E2 (phospho T392) antibody 画像

  • ab111369 at 1/100 dilution staining Cyclin E2 in NIH3T3 cells by Immunofluorescence. The image on the right is treated with the synthesized phosphopeptide.

Anti-Cyclin E2 (phospho T392) antibody (ab111369) 使用論文

ab111369 has not yet been referenced specifically in any publications.

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