Anti-Cyclin E1 (phospho T77) 抗体 (ab62199)

製品の概要

  • 製品名Anti-Cyclin E1 (phospho T77) antibody
    Cyclin E1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Cyclin E1 (phospho T77)
  • 特異性ab62199 detects endogenous levels of Cyclin E1 only when phosphorylated at threonine 77.
  • アプリケーション適用あり: ICC/IF, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide corresponding to Human Cyclin E1.

  • ポジティブ・コントロール
    • HeLa cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab62199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/500 - 1/1000.
ELISA 1/10000.

ターゲット情報

  • 機能Essential for the control of the cell cycle at the G1/S (start) transition.
  • 組織特異性Highly expressed in testis and placenta. Low levels in bronchial epithelial cells.
  • 配列類似性Belongs to the cyclin family. Cyclin E subfamily.
  • 翻訳後修飾Phosphorylation of Thr-395 by GSK3 and of Ser-399 by CDK2 accelerates degradation via the ubiquitin proteasome pathway. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CCNE antibody
    • Ccne1 antibody
    • CCNE1_HUMAN antibody
    • cyclin E variant ex5del antibody
    • cyclin E variant ex7del antibody
    • Cyclin E1 antibody
    • Cyclin Es antibody
    • Cyclin Et antibody
    • CyclinE antibody
    • G1/S specific cyclin E antibody
    • G1/S-specific cyclin-E1 antibody
    see all

Anti-Cyclin E1 (phospho T77) antibody 画像

  • Immunofluorescence analysis of HeLa cells using ab62199 at a dilution of 1/500. Samples were untreated (left hand panel) or treated (right hand panel) with the immunizing peptide.

Anti-Cyclin E1 (phospho T77) antibody (ab62199) 使用論文

ab62199 has not yet been referenced specifically in any publications.

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