製品の概要

  • 製品名Anti-Cyclin E1 antibody
    Cyclin E1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Cyclin E1
  • 特異性ab52239 detects endogenous levels of total Cyclin E1 protein.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to Human Cyclin E1. Immunogen range is 91-140

  • ポジティブ・コントロール
    • K562 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab52239 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/300 - 1/1000. Detects a band of approximately 49 kDa (predicted molecular weight: 47 kDa).
ELISA 1/20000.

ターゲット情報

  • 機能Essential for the control of the cell cycle at the G1/S (start) transition.
  • 組織特異性Highly expressed in testis and placenta. Low levels in bronchial epithelial cells.
  • 配列類似性Belongs to the cyclin family. Cyclin E subfamily.
  • 翻訳後修飾Phosphorylation of Thr-395 by GSK3 and of Ser-399 by CDK2 accelerates degradation via the ubiquitin proteasome pathway. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CCNE antibody
    • Ccne1 antibody
    • CCNE1_HUMAN antibody
    • cyclin E variant ex5del antibody
    • cyclin E variant ex7del antibody
    • Cyclin E1 antibody
    • Cyclin Es antibody
    • Cyclin Et antibody
    • CyclinE antibody
    • G1/S specific cyclin E antibody
    • G1/S-specific cyclin-E1 antibody
    see all

Anti-Cyclin E1 antibody 画像

  • All lanes : Anti-Cyclin E1 antibody (ab52239) at 1/300 dilution

    Lane 1 : K562 cell extract; without peptide
    Lane 2 : K562 cell extract; with peptide


    Predicted band size : 47 kDa
    Observed band size : 49 kDa (why is the actual band size different from the predicted?)

Anti-Cyclin E1 antibody (ab52239) 使用論文

ab52239 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab52239.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"