製品の概要

  • 製品名
    Anti-Cyclin A1 antibody [XLA1-3]
    Cyclin A1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [XLA1-3] to Cyclin A1
  • 特異性
    The antibody detects Xenopus cyclin A in blots. Cyclin A1 is the embryonic cyclin which is present in Xenopus eggs. Only detects Xenopus Cyclin A1.
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Xenopus laevis
  • 免疫原

    Full length protein.

  • 特記事項
    This product replaces ab10831.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab13337 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 2.5 µg/ml. Predicted molecular weight: 59 kDa.

ターゲット情報

  • 機能
    May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
  • 組織特異性
    Very high levels in testis and very low levels in brain. Also found in myeloid Leukemia cell lines.
  • 配列類似性
    Belongs to the cyclin family. Cyclin AB subfamily.
  • 発生段階
    Expression increases in early G1 phase and reaches highest levels during the S and G2/M phases.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
    • 別名
      • CCN A1 antibody
      • CCNA 1 antibody
      • Ccna1 antibody
      • CCNA1_HUMAN antibody
      • Cyclin-A1 antibody
      • CyclinA1 antibody
      • G2/mitotic specific cyclin A1 antibody
      • MGC132235 antibody
      • MGC159139 antibody
      see all

    プロトコール

    参考文献

    This product has been referenced in:
    • Stiles J  et al. Propranolol treatment of infantile hemangioma endothelial cells: A molecular analysis. Exp Ther Med 4:594-604 (2012). WB . Read more (PubMed: 23170111) »
    • Krasinska L  et al. Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus. EMBO J 27:758-69 (2008). Xenopus laevis . Read more (PubMed: 18256689) »

    See all 2 Publications for this product

    レビューと Q&A

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Xenopus laevis Tissue lysate - other (1 embryo per line)
    Loading amount
    1 cells
    Specification
    1 embryo per line
    Gel Running Conditions
    Non-reduced Non-Denaturing (Native) (4-12%)
    Blocking step
    Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Username

    Dr. Jolanta Kisielewska

    Verified customer

    投稿 Apr 13 2010

    Thank you for your enquiry regarding our cyclin A1 antibodies. Ab13337 is specific against xenopus cyclin A1 as it was raised against the whole protein from xenopus laevis. As there is about 60% homology between human and xenopus cyclin A1 the antibo...

    Read More

    Ab13337 was raised against Xenopus Cyclin A1. If you have any more questions, please contact us again.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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