製品の概要

  • 製品名
    Anti-CXCR6 antibody
    CXCR6 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to CXCR6
  • 由来種
    Goat
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Dog
  • 免疫原

    Synthetic peptide:

    SEDNSKTFSASHN

    with a Cysteine residue linker, corresponding to C terminal amino acids 321-333 of Human Bonzo (NP_006555.1).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • ポジティブ･コントロール
    • Human thymus tissue; HEK293 lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125115 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 39 kDa.Can be blocked with CXCR6 peptide (ab8388).
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
  • 組織特異性
    Expressed in lymphoid tissues and activated T cells.
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
    • 別名
      • bonzo antibody
      • C X C chemokine receptor type 6 antibody
      • C-X-C chemokine receptor type 6 antibody
      • CD 186 antibody
      • CD186 antibody
      • CD186 antigen antibody
      • CDw186 antibody
      • Chemokine (C X C motif) receptor 6 antibody
      • Chemokine C X C motif receptor 6 antibody
      • Chemokine CXC motif receptor 6 antibody
      • Chemokine receptor 6 antibody
      • CXC chemokine receptor type 6 antibody
      • CXC R6 antibody
      • CXC-R6 antibody
      • CXCR 6 antibody
      • CXCR-6 antibody
      • CXCR6 antibody
      • CXCR6_HUMAN antibody
      • G protein coupled receptor antibody
      • G protein coupled receptor bonzo antibody
      • G protein coupled receptor STRL 33 antibody
      • G protein coupled receptor STRL33 antibody
      • G protein coupled receptor TYMSTR antibody
      • G-protein coupled receptor bonzo antibody
      • G-protein coupled receptor STRL33 antibody
      • STRL 33 antibody
      • STRL33 antibody
      • TYMSTR antibody
      see all

    画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bonzo antibody (ab125115)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Bonzo antibody (ab125115)

      ab125115, at 3.75µg/ml, staining CXCR6 in formalin-fixed, paraffin-embedded Human thymus tissue by Immunohistochemistry.

    • Western blot - Anti-Bonzo antibody (ab125115)
      Western blot - Anti-Bonzo antibody (ab125115)
      Anti-CXCR6 antibody (ab125115) at 1 µg/ml + HEK293 lysate (in RIPA buffer) at 35 µg

      Developed using the ECL technique.

      Predicted band size: 39 kDa


      Exposure time: 1 hour

    参考文献

    This product has been referenced in:
    • Hald SM  et al. Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival. BMC Cancer 15:441 (2015). IHC . Read more (PubMed: 26021984) »

    See 1 Publication for this product

    ab125115 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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