Anti-CXCR2 抗体 [MM0222-7J40] (ab89254)
Key features and details
- Mouse monoclonal [MM0222-7J40] to CXCR2
- Suitable for: IHC-Fr, Flow Cyt, WB, Neutralising
- Reacts with: Human
- Isotype: IgG2a
製品の概要
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製品名
Anti-CXCR2 antibody [MM0222-7J40]
CXCR2 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MM0222-7J40] to CXCR2 -
由来種
Mouse -
アプリケーション
適用あり: IHC-Fr, Flow Cyt, WB, Neutralisingmore details -
種交差性
交差種: Human -
免疫原
Human recombinant CXCR2
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ポジティブ・コントロール
- WB: Human placenta tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography. -
ポリ/モノ
モノクローナル -
クローン名
MM0222-7J40 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab89254の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-Fr |
Use at an assay dependent concentration.
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Flow Cyt |
Use at an assay dependent concentration.
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WB |
1/500 - 1/1000. Predicted molecular weight: 40 kDa.
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Neutralising |
Use at an assay dependent concentration.
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特記事項 |
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IHC-Fr
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. |
WB
1/500 - 1/1000. Predicted molecular weight: 40 kDa. |
Neutralising
Use at an assay dependent concentration. |
ターゲット情報
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機能
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
翻訳後修飾
Phosphorylated upon ligand binding; which is required for desensitization. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3579 Human
- Omim: 146928 Human
- SwissProt: P25025 Human
- Unigene: 846 Human
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別名
- C-X-C chemokine receptor type 2 antibody
- CD 182 antibody
- CD182 antibody
see all
画像
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Anti-CXCR2 antibody [MM0222-7J40] (ab89254) at 1/500 dilution + Human placenta tissue lysate
Predicted band size: 40 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted?
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (1)
ab89254 は 1 報の論文で使用されています。
- Strong MJ et al. Dura promotes metastatic potential in prostate cancer through the CXCR2 pathway. J Neurooncol 153:33-42 (2021). PubMed: 33835371