Anti-CXCR1 抗体 [MM0221-7D22] (ab89251)
Key features and details
- Mouse monoclonal [MM0221-7D22] to CXCR1
- Suitable for: IHC-Fr, Flow Cyt, WB, Neutralising
- Reacts with: Human
- Isotype: IgG2a
製品の概要
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製品名
Anti-CXCR1 antibody [MM0221-7D22]
CXCR1 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MM0221-7D22] to CXCR1 -
由来種
Mouse -
アプリケーション
適用あり: IHC-Fr, Flow Cyt, WB, Neutralisingmore details -
種交差性
交差種: Human -
免疫原
Human recombinant CXCR1
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ポジティブ・コントロール
- WB: Human placenta tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography. -
ポリ/モノ
モノクローナル -
クローン名
MM0221-7D22 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab89251の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-Fr |
Use at an assay dependent concentration.
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Flow Cyt |
Use at an assay dependent concentration.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
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WB |
1/500 - 1/1000. Predicted molecular weight: 40 kDa.
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Neutralising |
Use at an assay dependent concentration.
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特記事項 |
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IHC-Fr
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
WB
1/500 - 1/1000. Predicted molecular weight: 40 kDa. |
Neutralising
Use at an assay dependent concentration. |
ターゲット情報
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機能
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3577 Human
- Omim: 146929 Human
- SwissProt: P25024 Human
- Unigene: 194778 Human
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別名
- C C antibody
- C C CKR 1 antibody
- C-X-C chemokine receptor type 1 antibody
see all
画像
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (1)
ab89251 は 1 報の論文で使用されています。
- Liu TJ et al. CXC chemokine-7 inhibits growth and migration of oral tongue squamous cell carcinoma cells, mediated by the epithelial-mesenchymal transition signaling pathway. Mol Med Rep 16:6896-6903 (2017). PubMed: 28901471