Is unsuitable for Immunohistochemistry (PFA fixed).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
組織特異性Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
配列類似性Belongs to the intercrine alpha (chemokine CxC) family.
細胞内局在Cell membrane. Secreted. Also exists as a soluble form.