The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500. Predicted molecular weight: 27 kDa.
Is unsuitable for Immunohistochemistry (PFA fixed).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
Belongs to the intercrine alpha (chemokine CxC) family.
Cell membrane. Secreted. Also exists as a soluble form.