製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CXCL16
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 52-193 of Human CXCL16 (AAH17588).

  • ポジティブ・コントロール
    • A549, HepG2 whole cell lysate

法規制情報

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab101404 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 28 kDa.
IHC-P 1/100 - 1/500. Antigen retrieval is recommended using heat mediated 10mM Citrate buffer or Tris-EDTA buffer (pH: 8.0)

ターゲット情報

  • 機能
    Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
  • 組織特異性
    Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
  • 配列類似性
    Belongs to the intercrine alpha (chemokine CxC) family.
  • 翻訳後修飾
    Glycosylated.
  • 細胞内局在
    Cell membrane. Secreted. Also exists as a soluble form.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C-X-C motif chemokine 16 antibody
    • Chemokine (C X C motif) ligand 16 antibody
    • Chemokine, CXC motif, ligand 16 antibody
    • CXC chemokine ligand 16 antibody
    • Cxcl16 antibody
    • CXCLG16 antibody
    • CXL16_HUMAN antibody
    • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein antibody
    • SCYB16 antibody
    • Small inducible cytokine B16 precursor antibody
    • Small-inducible cytokine B16 antibody
    • SR-PSOX antibody
    • SRPSOX antibody
    • Transmembrane chemokine CXCL16 antibody
    • UNQ2759/PRO6714 antibody
    see all

画像

  • Anti-CXCL16 antibody (ab101404) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 28 kDa
  • Immunohistochemical analysis of paraffin-embedded H661 xenograft, using ab101404 at 1/100 dilution.

参考文献

This product has been referenced in:
  • Cho SW  et al. CXCL16 signaling mediated macrophage effects on tumor invasion of papillary thyroid carcinoma. Endocr Relat Cancer 23:113-24 (2016). Read more (PubMed: 26559672) »
  • Zhang R  et al. A CRISPR screen defines a signal peptide processing pathway required by flaviviruses. Nature 535:164-8 (2016). Read more (PubMed: 27383988) »

See all 6 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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