Anti-CX3CL1 抗体 (ab25091)
Key features and details
- Rabbit polyclonal to CX3CL1
- Suitable for: IP, WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-CX3CL1 antibody
CX3CL1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to CX3CL1 -
由来種
Rabbit -
特異性
ab25091 recognises CX3CL1 -
アプリケーション
適用あり: IP, WBmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant fragment: E. coli expressed chemotactic domain of mouse CX3CL1.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.1% Sodium azide
Constituent: 99.9% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab25091の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IP |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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特記事項 |
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IP
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. -
組織特異性
Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas. -
配列類似性
Belongs to the intercrine delta family. -
翻訳後修飾
A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.
O-glycosylated with core 1 or possibly core 8 glycans. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 20312 Mouse
- SwissProt: O35188 Mouse
- Unigene: 103711 Mouse
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別名
- A 152E5.2 antibody
- AB030188 antibody
- ABCD 3 antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab25091 は 2 報の論文で使用されています。
- Gong Q et al. Fractalkine aggravates LPS-induced macrophage activation and acute kidney injury via Wnt/ß-catenin signalling pathway. J Cell Mol Med 25:6963-6975 (2021). PubMed: 34101346
- Zhang Q et al. PSD-93 mediates the crosstalk between neuron and microglia and facilitates acute ischemic stroke injury by binding to CX3CL1. J Neurochem 157:2145-2157 (2021). PubMed: 33599284