製品の概要

  • 製品名Curcumin (Diferuloylmethane)
  • 製品の詳細
    Flavonoid. Lipooxygenase inhibitor. Antioxidant, anti-inflammatory agent.
  • 別名
    • Diferuloylmethane
  • 生理活性の詳細Flavonoid derived from Curcuma longa plant. Potent antioxidant, anti-inflammatory, analgesic and anticancer agent. Lipooxygenase and cyclooxygenase inhibitor (IC50 values are 8 and 52 μM, respectively). Blood-brain barrier permeable. Shows diverse range of actions including free radical scavenging activity in vitro and in vivo, cardio and neuroprotective effects.

製品の特性

    アプリケーション

    Our Abpromise guarantee covers the use of ab120618 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    アプリケーション Abreviews 特記事項
    Functional Studies Use at an assay dependent concentration.

    Curcumin (Diferuloylmethane) 画像

    • ab32137 staining c-Jun in HeLa cells treated with curcumin (diferuloylmethane) (ab120618), by ICC/IF. Decrease in c-Jun expression correlates with increased concentration of curcumin (diferuloylmethane) as described in literature.
      The cells were incubated at 37°C for 4h in media containing different concentrations of ab120618 (curcumin (diferuloylmethane)) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab32137 (1/100 dilution) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-rabbit polyclonal antibody (ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

    Curcumin (Diferuloylmethane) (ab120618) 使用論文

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