製品の概要

  • 製品名Anti-Cullin 7 antibody
    Cullin 7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Cullin 7
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids 1370-1679 of Human Cullin 7

  • ポジティブ・コントロール
    • H1299, HeLa, HepG2, Molt-4, Raji

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab96861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 191 kDa.

ターゲット情報

  • 機能Component of a probable SCF-like E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity). Seems not to promote polyubiquitination and proteasomal degradation of TP53. In vitro, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity.
  • 組織特異性Highly expressed in fetal kidney and adult skeletal muscle. Also abundant in fetal brain, as well as in adult pancreas, kidney, placenta and heart. Detected in trophoblasts, lymphoblasts, osteoblasts, chondrocytes and skin fibroblasts.
  • パスウェイProtein modification; protein ubiquitination.
  • 関連疾患Defects in CUL7 are the cause of 3M syndrome type 1 (3M1) [MIM:273750]. An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, and normal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebral bodies.
  • 配列類似性Belongs to the cullin family.
    Contains 1 DOC domain.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CUL-7 antibody
    • CUL7 antibody
    • CUL7_HUMAN antibody
    • Cullin-7 antibody
    • dJ20C7.5 antibody
    • KIAA0076 antibody
    see all

Anti-Cullin 7 antibody 画像

  • Anti-Cullin 7 antibody (ab96861) at 1/1000 dilution + Molt-4 cell lysate at 30 µg

    Predicted band size : 191 kDa

Anti-Cullin 7 antibody (ab96861) 使用論文

ab96861 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab96861.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"