製品の概要

  • 製品名Anti-CTRP4 antibody
    CTRP4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CTRP4
  • アプリケーション適用あり: WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A 16 amino acid peptide from near the carboxy terminus of human CTRP4.

  • ポジティブ・コントロール
    • Rat brain cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab36871 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 37 kDa).Can be blocked with Human CTRP4 peptide (ab39741).
IHC-P Use a concentration of 10 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.

ターゲット情報

  • 関連性Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported.
  • 細胞内局在Secreted
  • 参照データベース
  • 別名
    • C1q and tumor necrosis factor related protein 4 antibody
    • C1QTNF4 antibody
    • Complement C1q tumor necrosis factor related protein antibody
    • ZACRP4 antibody

Anti-CTRP4 antibody 画像

  • Lane 1 : Anti-CTRP4 antibody (ab36871) at 1 µg/ml
    Lane 2 : Anti-CTRP4 antibody (ab36871) at 2 µg/ml
    Lane 3 : Anti-CTRP4 antibody (ab36871) at 4 µg/ml

    Lane 1 : Rat brain cell lysate
    Lane 2 : Rat brain cell lysate
    Lane 3 : Rat brain cell lysate

    Lysates/proteins at 15 µg/ml per lane.

    Secondary
    anti-rabbit IgG HRP at 1/10000 dilution

    Predicted band size : 37 kDa
    Observed band size : 35 kDa (why is the actual band size different from the predicted?)
    Lanes read from left to right 1, 2 and 3. These proteins are often highly modified post-translationally and may migrate in SDS-PAGE at positions other than their predicted size.
  • ab36891 at 10µg/ml staining CTRP4 in rat brain by IHC

  • Immunofluorescence of CTRP4 in Rat Brain cells using ab36871 at 20 ug/ml.

Anti-CTRP4 antibody (ab36871) 使用論文

This product has been referenced in:
  • Byerly MS  et al. C1q/TNF-related protein 4 (CTRP4) is a unique secreted protein with two tandem C1q domains that functions in the hypothalamus to modulate food intake and body weight. J Biol Chem 289:4055-69 (2014). WB ; Mouse . Read more (PubMed: 24366864) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"