製品の概要

  • 製品名Anti-CTDSP1 antibody - C-terminal
    CTDSP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CTDSP1 - C-terminal
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    KLH conjugated synthetic peptide selected from the C terminal region of human CTDSP1 protein.

  • ポジティブ・コントロール
    • CEM tissue lysate. 293 cell lysates transiently transfected with the CTDSP1 gene. Human hepatocarcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab76099 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 29 kDa.
ELISA 1/1000.
IHC-P 1/50 - 1/100.

ターゲット情報

  • 機能Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
  • 組織特異性Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
  • 配列類似性Contains 1 FCP1 homology domain.
  • 細胞内局在Nucleus. Colocalizes with RNA polymerase II.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody
    • Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody
    • CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1 antibody
    • CTDS1_HUMAN antibody
    • CTDSP1 antibody
    • NIF3 antibody
    • NLI IF antibody
    • NLI interacting factor 3 antibody
    • NLI-IF antibody
    • NLI-interacting factor 3 antibody
    • NLIIF antibody
    • Nuclear LIM interactor interacting factor 3 antibody
    • Nuclear LIM interactor-interacting factor 3 antibody
    • SCP1 antibody
    • Small C-terminal domain phosphatase 1 antibody
    • Small CTD phosphatase 1 antibody
    see all

Anti-CTDSP1 antibody - C-terminal 画像

  • Anti-CTDSP1 antibody - C-terminal (ab76099) at 1/100 dilution + CEM tissue lysate at 12.5 µg

    Predicted band size : 29 kDa
    Observed band size : 33 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 25 kDa,60 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-CTDSP1 antibody - C-terminal (ab76099) at 1/100 dilution

    Lane 1 : Nontransfected 293 cell lysates
    Lane 2 : 293 cell lysates transiently transfected with the CTDSP1 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 29 kDa
    Observed band size : 33 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 72 kDa. We are unsure as to the identity of these extra bands.
  • ab76099, at 1/50 dilution, staining CTDSP1 in formalin-fixed, paraffin-embedded human hepatocarcinoma tissue by Immunohistochemistry, followed by a peroxidase conjugated secondary antibody and DAB staining.

Anti-CTDSP1 antibody - C-terminal (ab76099) 使用論文

ab76099 has not yet been referenced specifically in any publications.

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