製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CtBP1
  • アプリケーション
    適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Zebrafish
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 194 and 349 of Human CtBP1 (NP_001319).

  • ポジティブ・コントロール
    • HeLa whole cell lysate, Molt-4 cell lysate.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab97392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能
    Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.
  • 配列類似性
    Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  • 翻訳後修飾
    The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.
    ADP-ribosylated; when cells are exposed to brefeldin A.
    Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.
  • 細胞内局在
    Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BARS antibody
    • brefeldin A- ribosylated substrate antibody
    • C terminal binding protein 1 antibody
    • C-terminal-binding protein 1 antibody
    • CTBP antibody
    • CtBP1 antibody
    • CTBP1_HUMAN antibody
    • MGC104684 antibody
    see all

画像

  • Anti-CtBP1 antibody (ab97392) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 48 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using CtBP1 antibody (ab97392) at 1/200 dilution. Lower image merged with DNA probe.

参考文献

ab97392 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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