製品の概要

  • 製品名Anti-CtBP1 antibody
    CtBP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CtBP1
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Chicken, Cat, Dog, Pig
  • 免疫原

    A region within synthetic peptide IPAAVEGIVP SAMSLSHGLP PVAHPPHAPS PGQTVKPEAD RDHASDQL, corresponding to C terminal amino acids 382-429 of Human CtBP1

  • ポジティブ・コントロール
    • Jurkat cell lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab49194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 47 kDa (predicted molecular weight: 49 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA 1/62500.

ターゲット情報

  • 機能Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.
  • 配列類似性Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  • 翻訳後修飾The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.
    ADP-ribosylated; when cells are exposed to brefeldin A.
    Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BARS antibody
    • brefeldin A- ribosylated substrate antibody
    • C terminal binding protein 1 antibody
    • C-terminal-binding protein 1 antibody
    • CTBP antibody
    • CtBP1 antibody
    • CTBP1_HUMAN antibody
    • MGC104684 antibody
    see all

Anti-CtBP1 antibody 画像

  • Anti-CtBP1 antibody (ab49194) at 1.25 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 49 kDa
    Observed band size : 47 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemistry of Human Pancreas lysate tissue at an antibody concentration of 4-8µg/ml using anti-CTBP1 antibody (ab49194)

Anti-CtBP1 antibody (ab49194) 使用論文

ab49194 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"