製品の概要

  • 製品名CTAP
  • 製品の詳細
    Potent, selective μ opioid antagonist
  • 生理活性の詳細Potent and selective μ opioid receptor antagonist (1200-fold more selective vs. δ receptor). Blood-brain barrier permeable and active in vivo. Antagonizes antinociceptive effect.

製品の特性

    CTAP (ab120680) 使用論文

    This product has been referenced in:
    • Steinmiller CL & Young AM Pharmacological selectivity of CTAP in a warm water tail-withdrawal antinociception assay in rats. Psychopharmacology (Berl) 195:497-507 (2008). Read more (PubMed: 17882404) »
    • Sterious SN & Walker EA Potency differences for D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 as an antagonist of peptide and alkaloid micro-agonists in an antinociception assay. J Pharmacol Exp Ther 304:301-9 (2003). Read more (PubMed: 12490605) »
    • Abbruscato TJ  et al. Blood-brain barrier permeability and bioavailability of a highly potent and mu-selective opioid receptor antagonist, CTAP: comparison with morphine. J Pharmacol Exp Ther 280:402-9 (1997). Read more (PubMed: 8996221) »

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