製品の概要

  • 製品名Anti-CSN7b antibody
    CSN7b 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to CSN7b
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human CSN7b (NP_073567.1, amino acids 1-264)

  • ポジティブ・コントロール
    • HeLa cell lysate, CSN7b transfected 293T cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab89645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa.

ターゲット情報

  • 機能Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
  • 配列類似性Belongs to the CSN7/EIF3M family. CSN7 subfamily.
    Contains 1 PCI domain.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • COP9 Complex Homolog Subunit 7b antibody
    • COP9 Constitutive Photomorphogenic Homolog Subunit 7b antibody
    • COP9 Signalasome Subunit 7b antibody
    • COP9 signalosome complex subunit 7b antibody
    • COPS7B antibody
    • CSN7B_HUMAN antibody
    • JAB1 Containing Signalosome Subunit 7b antibody
    • JAB1-containing signalosome subunit 7b antibody
    • SGN7b antibody
    • Signalosome subunit 7b antibody
    see all

Anti-CSN7b antibody 画像

  • Anti-CSN7b antibody (ab89645) at 1 µg/ml + HeLa cell lysate at 50 µg

    Predicted band size : 32 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-CSN7b antibody (ab89645) at 1 µg/ml

    Lane 1 : CSN7b transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 32 kDa
    Observed band size : 32 kDa

Anti-CSN7b antibody (ab89645) 使用論文

ab89645 has not yet been referenced specifically in any publications.

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