製品の概要

  • 製品名Anti-CSN3 antibody
    CSN3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CSN3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MKSFLLVVNA LALTLPFLAV EVQNQKQPAC HENDERPFYQ KTAPYVPMYY) of Human CSN3 (NP_005203).

  • ポジティブ・コントロール
    • Jurkat cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 20 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性CSN3 is a component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
  • 細胞内局在Secreted
  • 参照データベース
  • 別名
    • Casein Kappa antibody
    • COP9 Signalosome Complex Subunit 3 antibody
    • COPS3 antibody
    • CSN10 antibody
    • CSNK antibody
    • JAB1 Containing Signalosome Subunit 3 antibody
    • kappa-casein antibody
    • KCA antibody
    • SGN3 antibody
    • Signalosome Subunit 3 antibody
    see all

Anti-CSN3 antibody 画像

  • Anti-CSN3 antibody (ab111406) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 20 kDa

Anti-CSN3 antibody (ab111406) 使用論文

ab111406 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"