製品の概要

  • 製品名
    Anti-CRYZ antibody [2A9DD1]
    CRYZ 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2A9DD1] to CRYZ
  • アプリケーション
    適用あり: ICC/IF, IP, In-Cell ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Tissue, cells or virus corresponding to CRYZ. Human liver mitochondria.

  • ポジティブ・コントロール
    • HeLa cells; Human liver and HepG2 lysates.
  • 特記事項

    This antibody clone is manufactured by Abcam.

    Product was previously marketed under the MitoSciences sub-brand.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 2 µg/ml. For 2 hours.
IP Use at an assay dependent dilution.
In-Cell ELISA Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
  • 組織特異性
    Only very low amounts in the lens.
  • 配列類似性
    Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Crystallin zeta (quinone reductase) antibody
    • Crystallin zeta antibody
    • Cryz antibody
    • DKFZp779E0834 antibody
    • FLJ41475 antibody
    • NADPH:quinone reductase antibody
    • QOR_HUMAN antibody
    • Quinone oxidoreductase antibody
    • Zeta crystallin antibody
    • Zeta-crystallin antibody
    see all

画像

  • Immunocytochemistry analysis using ab110310 at 2µg/ml staining CRYZ in HELa cells (4% paraformaldehyde fixed and 0.1% Triton X-100 permeabilized) followed by Alexa Fluor® 488 goat anti-mouse IgG (H+L) used at a 1/1000 dilution for 1 hour (green).
  • Using MitoSciences' standard immunoprecipitation protocol, ab110310 precipitates the 35kDa CRYZ protein from human liver and HepG2 lysate. Identity of this protein was confirmed by mass spectrometry. This gel was stained with silver nitrate.

参考文献

ab110310 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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