製品の概要

  • 製品名Anti-CRYBB3 antibody
    CRYBB3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to CRYBB3
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性

    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment: PHHKLHLFEN PAFSGRKMEI VDDDVPSLWA HGFQDRVASV RAINGTWVGY EFPGYRGRQY VFERGEYRHW NEWDASQPQL QSVRRIRDQK WHKRGRFPSS , corresponding to amino acids 112-212 of Human CRYBB3, with tag (NP_004067)

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab76642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 24 kDa.
    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Crystallins are the dominant structural components of the vertebrate eye lens.
    • 関連疾患Defects in CRYBB3 are the cause of cataract congenital nuclear autosomal recessive type 2 (CATCN2) [MIM:609741]. A congenital cataract affecting the central nucleus of the eye. Nuclear cataracts are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders.
    • 配列類似性Belongs to the beta/gamma-crystallin family.
      Contains 4 beta/gamma crystallin 'Greek key' domains.
    • ドメインHas a two-domain beta-structure, folded into four very similar Greek key motifs.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Beta B3 crystallin antibody
      • Beta crystallin B3 antibody
      • Beta-B3 crystallin antibody
      • Beta-crystallin B3 antibody
      • CRBB3_HUMAN antibody
      • CRYB3 antibody
      • Crybb3 antibody
      see all

    Anti-CRYBB3 antibody 画像

    • Anti-CRYBB3 antibody (ab76642) at 5 µg/ml + immunogen at 0.2 µg

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

      Predicted band size : 24 kDa
      Observed band size : 36 kDa (why is the actual band size different from the predicted?)

    Anti-CRYBB3 antibody (ab76642) 使用論文

    ab76642 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab76642.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"