製品の概要

  • 製品名Anti-CRYBA4 antibody
    CRYBA4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CRYBA4
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Guinea pig, Cow, Dog, Pig, Monkey
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 1 - 150 of Human CRYBA4 (NP_001877).

  • ポジティブ・コントロール
    • WB: 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lyates IF: HeLa cells

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab97771 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 22 kDa.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能Crystallins are the dominant structural components of the vertebrate eye lens.
  • 関連疾患Defects in CRYBA4 are the cause of cataract zonular type 2 (CZ2) [MIM:610425]; also known as lamellar cataract 2. A form of zonular cataract. Zonular or lamellar cataracts are opacities, broad or narrow, usually consisting of powdery white dots affecting only certain layers or zones between the cortex and nucleus of an otherwise clear lens. The opacity may be so dense as to render the entire central region of the lens completely opaque, or so translucent that vision is hardly if at all impeded. Zonular cataracts generally do not involve the embryonic nucleus, though sometimes they involve the fetal nucleus. Usually sharply separated from a clear cortex outside them, they may have projections from their outer edges known as riders or spokes.
    Defects in CRYBA4 are a cause of microphthalmia isolated with cataract type 4 (MCOPCT4) [MIM:610426]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present.
  • 配列類似性Belongs to the beta/gamma-crystallin family.
    Contains 4 beta/gamma crystallin 'Greek key' domains.
  • ドメインHas a two-domain beta-structure, folded into four very similar Greek key motifs.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Beta A4 crystallin antibody
    • Beta crystallin A4 antibody
    • Beta-A4 crystallin antibody
    • Beta-crystallin A4 antibody
    • CRBA4_HUMAN antibody
    • CRYBA4 antibody
    • Crystallin beta A4 antibody
    • Crystallin, beta polypeptide A4 antibody
    • Eye lens structural protein antibody
    • MCOPCT4 antibody
    see all

Anti-CRYBA4 antibody 画像

  • All lanes : Anti-CRYBA4 antibody (ab97771) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 22 kDa
  • ab97771, at a 1/200 dilution, staining CRYBA4 in paraformaldehyde-fixed HeLa by Immunofluorescence analysis. Right image is merged with a DNA probe.

Anti-CRYBA4 antibody (ab97771) 使用論文

ab97771 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"