製品の概要

  • 製品名Anti-CRY2 antibody
    CRY2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CRY2
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 543-593 of Human CRY2 (AAH41814.1)

  • ポジティブ・コントロール
    • Whole cell lysate from HeLa and 293T cells

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab93802 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
  • 追加情報IP: Use at 2-5µg/mg of lysate.
    WB: 1/2000 - 1/10,000. Predicted molecular weight: 67 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK
      NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK
      NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
    • 組織特異性Expressed in all tissues examined including fetal brain, fibroblasts, heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Highest levels in heart and skeletal muscle.
    • 配列類似性Belongs to the DNA photolyase class-1 family.
      Contains 1 DNA photolyase domain.
    • 翻訳後修飾Phosphorylation on Ser-266 by MAPK is important for the inhibition of CLOCK-ARNTL-mediated transcriptional activity. Phosphorylation by CSKNE requires interaction with PER1 or PER2.
      Ubiquitinated by the SCF(FBXL3) and SCF(FBXL21) complex, leading to its degradation.
    • 細胞内局在Cytoplasm. Nucleus. Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL.
    • Information by UniProt
    • 参照データベース
    • 別名
      • cry2 antibody
      • CRY2_HUMAN antibody
      • cryptochrome 2 (photolyase like) antibody
      • Cryptochrome 2 antibody
      • Cryptochrome-2 antibody
      • FLJ10332 antibody
      • growth inhibiting protein 37 antibody
      • HCRY2 antibody
      • KIAA0658 antibody
      • PHLL2 antibody
      • Photolyase like antibody
      see all

    Anti-CRY2 antibody 画像

    • All lanes : Anti-CRY2 antibody (ab93802) at 0.04 µg/ml

      Lane 1 : whole HeLa cell lysate at 50 µg
      Lane 2 : whole HeLa cell lysate at 15 µg
      Lane 3 : whole HeLa cell lysate at 5 µg
      Lane 4 : whole 293T cell lysate at 50 µg


      Predicted band size : 67 kDa
    • Immunoprecipitation analysis of CRY2 expression in whole HeLa cells lysate (1 mg for IP, 20% of IP loaded) using ab93802 at 3 ug/mg lysate (Left Lane). Right lane represent IP antibody control. Subsequent WB analysis was performed using 1ug/ml ab93802.

    Anti-CRY2 antibody (ab93802) 使用論文

    ab93802 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab93802.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"