製品の概要

  • 製品名
    Anti-Crry antibody [TLD-1C11] (FITC)
    Crry 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [TLD-1C11] to Crry (FITC)
  • 標識
    FITC. Ex: 493nm, Em: 528nm
  • 特異性
    ab106109 can be used to block autoimmune phenomena in rats.
  • アプリケーション
    適用あり: WB, IHC-Fr, Functional Studies, Flow Cyt, ICC/IF, ELISAmore details
  • 種交差性
    交差種: Rat
  • 免疫原

    Rat microglial cells

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    Preservative: None
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    0.2 µm filtered antibody solution
  • ポリ/モノ
    モノクローナル
  • クローン名
    TLD-1C11
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab106109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 62 kDa.
IHC-Fr Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab91356-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
ICC/IF Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Seems to act as a costimulatory factor for T-cells. May play a crucial role in early embryonic development by maintaining fetomaternal tolerance.
  • 配列類似性
    Contains 7 Sushi (CCP/SCR) domains.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Antigen 5I2 antibody
    • Complement C4b binding protein CR 1 like protein antibody
    • Complement component (3b/4b) receptor 1 like antibody
    • Complement component receptor 1 like protein antibody
    • Complement regulatory protein Crry antibody
    • CR1L antibody
    • Crry antibody
    • CRRY_RAT antibody
    • MGC129536 antibody
    see all

参考文献

This product has been referenced in:
  • Huang G  et al. Characterization of transfusion-elicited acute antibody-mediated rejection in a rat model of kidney transplantation. Am J Transplant 14:1061-72 (2014). Read more (PubMed: 24708533) »
  • Fraser DA  et al. Bacterial expression and membrane targeting of the rat complement regulator Crry: a new model anticomplement therapeutic. Protein Sci 11:2512-21 (2002). Read more (PubMed: 12237472) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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