製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CROP
  • アプリケーション
    適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 200 and 250 of human CROP (NP_057508.2).

  • ポジティブ・コントロール
    • Whole cell lysate from HeLa cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab80415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP
  • 追加情報
    IP: Use at 2 - 5 µg/mg of lysate.

    Is unsuitable for WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing.
    • 組織特異性
      Widely expressed. Highest levels in heart, brain, pancreas, thymus, ovary, small intestine and peripheral blood leukocytes, as well as cerebellum, putamen and pituitary gland. Lowest levels in lung, liver and kidney. Also expressed in fetal tissues, including brain, heart, kidney, thymus and lung.
    • 配列類似性
      Belongs to the Luc7 family.
    • 翻訳後修飾
      Phosphorylated in vitro by SRPK1, SRPK2 and CLK1.
    • 細胞内局在
      Nucleus speckle. The subnuclear localization is affected by cisplatin.
    • Information by UniProt
    • 参照データベース
    • 別名
      • cAMP regulatory element-associated protein 1 antibody
      • Cisplatin resistance-associated overexpressed protein antibody
      • Cisplatin resistance-associated-overexpressed protein antibody
      • CRA antibody
      • CRE-associated protein 1 antibody
      • CREAP-1 antibody
      • CREAP1 antibody
      • CROP antibody
      • hLuc7A antibody
      • LC7L3_HUMAN antibody
      • LUC7 like 3 pre mRNA splicing factor antibody
      • Luc7-like protein 3 antibody
      • Luc7A antibody
      • LUC7L3 antibody
      • O48 antibody
      • OA48 18 antibody
      • Okadaic acid-inducible phosphoprotein OA48-18 antibody
      see all

    画像

    • Detection of human CROP in Immunoprecipitates of whole cell lysate from HeLa cells (1 mg for IP, 20% of IP loaded) using ab80415 at 3 µg/mg lysate for IP (lane 1). Lane 2 represents control IgG IP. Subsequent WB detection used ab80412 (which recognizes an upstream epitope) at 1 µg/ml.

    プロトコール

    参考文献

    ab80415 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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