製品の概要

  • 製品名Anti-CRLF2 antibody
    CRLF2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to CRLF2
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 23-133 of Human CRLF2

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab56373 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 42 kDa.
ICC/IF Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.
  • 組織特異性Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.
  • 配列類似性Belongs to the type I cytokine receptor family. Type 5 subfamily.
    Contains 1 fibronectin type-III domain.
  • ドメインThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is important for association with JAKs.
  • 細胞内局在Secreted and Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CRL 2 antibody
    • CRL2 antibody
    • CRLF 2 antibody
    • Crlf2 antibody
    • CRLF2_HUMAN antibody
    • CRLF2Y antibody
    • Cytokine receptor CRL2 precusor antibody
    • Cytokine receptor like 2 antibody
    • Cytokine receptor like factor 2 antibody
    • Cytokine receptor like factor 2 precursor antibody
    • Cytokine receptor-like 2 antibody
    • Cytokine receptor-like factor 2 antibody
    • IL XR antibody
    • IL-XR antibody
    • ILXR antibody
    • Thymic stromal derived lymphopoietin receptor antibody
    • Thymic stromal lymphopoietin protein receptor antibody
    • Thymic stromal lymphopoietin receptor antibody
    • TSLP receptor antibody
    • TSLPR antibody
    see all

Anti-CRLF2 antibody 画像



  • Predicted band size : 42 kDa
    CRLF2 antibody (ab56373) at 1ug/lane + HeLa cell lysate at 25ug/lane.
  • ICC/IF image of ab56373 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab56373, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96879, DyLight® 488 goat anti-mouse IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-CRLF2 antibody (ab56373) 使用論文

ab56373 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"