製品の概要

  • 製品名Anti-CRLF2 antibody
    CRLF2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CRLF2
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide of 19 amino acids in length from near the center of Human CRLF2.

  • ポジティブ・コントロール
    • Human liver tissue, Human kidney tissue

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab109626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.
  • 組織特異性Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.
  • 配列類似性Belongs to the type I cytokine receptor family. Type 5 subfamily.
    Contains 1 fibronectin type-III domain.
  • ドメインThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is important for association with JAKs.
  • 細胞内局在Secreted and Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CRL 2 antibody
    • CRL2 antibody
    • CRLF 2 antibody
    • Crlf2 antibody
    • CRLF2_HUMAN antibody
    • CRLF2Y antibody
    • Cytokine receptor CRL2 precusor antibody
    • Cytokine receptor like 2 antibody
    • Cytokine receptor like factor 2 antibody
    • Cytokine receptor like factor 2 precursor antibody
    • Cytokine receptor-like 2 antibody
    • Cytokine receptor-like factor 2 antibody
    • IL XR antibody
    • IL-XR antibody
    • ILXR antibody
    • Thymic stromal derived lymphopoietin receptor antibody
    • Thymic stromal lymphopoietin protein receptor antibody
    • Thymic stromal lymphopoietin receptor antibody
    • TSLP receptor antibody
    • TSLPR antibody
    see all

Anti-CRLF2 antibody 画像

  • Lane 1 : Anti-CRLF2 antibody (ab109626) at 0.5 µg/ml
    Lane 2 : Anti-CRLF2 antibody (ab109626) at 1 µg/ml
    Lane 3 : Anti-CRLF2 antibody (ab109626) at 2 µg/ml

    Lane 1 : Human liver tissue lysate
    Lane 2 : Human liver tissue lysate
    Lane 3 : Human liver tissue lysate


    Predicted band size : 42 kDa
  • Human kidney tissue (formalin-fixed, paraffin-embedded) stained with ab109626 at a concentration of 5 µg/ml.
  • Human liver tissue (formalin-fixed, paraffin-embedded) stained with ab109626 at a concentration of 5 µg/ml.

Anti-CRLF2 antibody (ab109626) 使用論文

ab109626 has not yet been referenced specifically in any publications.

Product Wall

ab109626 is raised against the extracellular portion of human CRLF2 according to uniprot (http://www.uniprot.org/uniprot/Q9HC73). The immunogenic peptide used to generate this antibody is located between amino acids 125 and 175 of Q9HC73. There is also...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"