リコンビナント
RabMAb

Anti-CrkL 抗体 [Y244] (ab32018)

製品の概要

  • 製品名
    Anti-CrkL antibody [Y244]
    CrkL 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [Y244] to CrkL
  • 特異性
    ab32018 recognises CrkL (Crk-like)protein.
  • アプリケーション
    適用あり: WB, IHC-P, ICC, IPmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to residues in the second SH3 domain and near C terminus of human Crk like protein

  • ポジティブ・コントロール
    • K562 cell lysate, human metastatic lung carcinoma
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

     

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab32018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500. Detects a band of approximately 36 kDa (predicted molecular weight: 33 kDa).
IHC-P Use at an assay dependent concentration.
ICC 1/50.
IP 1/10.

ターゲット情報

  • 機能
    May mediate the transduction of intracellular signals.
  • 配列類似性
    Belongs to the CRK family.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Crk L antibody
    • Crk like protein antibody
    • Crk-like protein antibody
    • Crkl antibody
    • CRKL_HUMAN antibody
    • Crkol antibody
    • HGNC:2363 antibody
    • Oncogene CrkL antibody
    • V crk avian sarcoma virus CT10 oncogene homolog like antibody
    • v crk sarcoma virus CT10 oncogene homolog (avian) like antibody
    • V crk sarcoma virus CT10 oncogene homolog avian like antibody
    see all

画像

  • Anti-CrkL antibody [Y244] (ab32018) at 1/500 dilution + K562 cell lysate

    Predicted band size : 33 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • ab32018, at a 1/50 dilution, staining human Crk in metastatic lung carcinoma by Immunohistochemistry, in paraffin embedded tissue

参考文献

This product has been referenced in:
  • Hutchinson CV  et al. Lymphocytes from chronic lymphocytic leukaemia undergo ABL1-linked amoeboid motility and homotypic interaction as an early adaptive change to ex vivo culture. Exp Hematol Oncol 3:7 (2014). Read more (PubMed: 24618035) »

See 1 Publication for this product

レビューと Q&A

Thank you for your inquiry. I have confirmed that neither of these two anti-CrkL antibodies, ab32018 or ab32126, bind within the region a.a. 123 - 183 (the first SH3 domain). I apologize but it doesn't look like any of the anti-CrkL ant...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録