The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.5 µg/ml. Predicted molecular weight: 47 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
機能Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci.
配列類似性Belongs to the bZIP family. CREBRF subfamily. Contains 1 bZIP (basic-leucine zipper) domain.
翻訳後修飾Probably degraded by the proteasome.
細胞内局在Nucleus. Colocalizes with CREB3 in nuclear foci.