製品の概要

  • 製品名Anti-CPT2 antibody - N-terminal
    CPT2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CPT2 - N-terminal
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide from the N-terminal region of Human CPT2, conjugated to KLH.

  • ポジティブ・コントロール
    • HepG2 cell line lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab71293 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 65 kDa (predicted molecular weight: 74 kDa).

ターゲット情報

  • パスウェイLipid metabolism; fatty acid beta-oxidation.
  • 関連疾患Defects in CPT2 are the cause of carnitine palmitoyltransferase 2 deficiency (CPT2D) [MIM:255110, 600649]; also known as CPT-II deficiency or CPT2 deficiency. CPT2D is an autosomal recessive disorder characterized by recurrent myoglobinuria, episodes of muscle pain, stiffness, and rhabdomyolysis. These symptoms are triggered by prolonged exercise, fasting or viral infection and patients are usually young adults. In addition to this classical, late-onset, muscular type, a hepatic or hepatocardiomuscular form has been reported in infants. Clinical pictures in these children or neonates include hypoketotic hypoglycemia, liver dysfunction, cardiomyopathy and sudden death.
    Defects in CPT2 are the cause of carnitine palmitoyltransferase 2 deficiency, lethal neonatal (CPT2D-LN) [MIM:608836]; also known as lethal neonatal CPT-II deficiency. It is a lethal neonatal form of CPT2D. This rarely presentation is antenatal with cerebral periventricular cysts and cystic dysplastic kidneys. The clinical variability of the disease is likely attributed to the variable residual enzymatic activity.
  • 配列類似性Belongs to the carnitine/choline acetyltransferase family.
  • 細胞内局在Mitochondrion inner membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Carnitine O palmitoyltransferase 2 antibody
    • Carnitine O palmitoyltransferase 2 mitochondrial antibody
    • Carnitine O-palmitoyltransferase 2 antibody
    • Carnitine palmitoyltransferase 2 antibody
    • Carnitine palmitoyltransferase II antibody
    • CPT 1 antibody
    • CPT 2 antibody
    • CPT II antibody
    • CPT1 antibody
    • CPT2 antibody
    • CPT2_HUMAN antibody
    • CPTASE antibody
    • CPTII antibody
    • IIAE4 antibody
    • mitochondrial antibody
    see all

Anti-CPT2 antibody - N-terminal 画像

  • Anti-CPT2 antibody - N-terminal (ab71293) at 1/100 dilution + HepG2 cell line lysate at 35 µg

    Predicted band size : 74 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 19 kDa,26 kDa,28 kDa,50 kDa,58 kDa. We are unsure as to the identity of these extra bands.

Anti-CPT2 antibody - N-terminal (ab71293) 使用論文

ab71293 has not yet been referenced specifically in any publications.

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