製品の概要

  • 製品名Anti-CPT1A antibody
    CPT1A 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to CPT1A
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    C-DPAQTVEQRLKLFK

    , corresponding to internal sequence amino acids 621-634 of Human CPT1A

  • ポジティブ・コントロール
    • Human Liver lysate

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 80 kDa (predicted molecular weight: 86 kDa).
IHC-P Use a concentration of 4 - 6 µg/ml.

ターゲット情報

  • 組織特異性Strong expression in kidney and heart, and lower in liver and skeletal muscle.
  • パスウェイLipid metabolism; fatty acid beta-oxidation.
  • 関連疾患Defects in CPT1A are the cause of carnitine palmitoyltransferase 1A deficiency (CPT1AD) [MIM:255120]; also known as CPT-I deficiency or CPT1A deficiency. CPT1AD is a rare autosomal recessive metabolic disorder of long-chain fatty acid oxidation characterized by severe episodes of hypoketotic hypoglycemia usually occurring after fasting or illness. Onset is in infancy or early childhood.
  • 配列類似性Belongs to the carnitine/choline acetyltransferase family.
  • 細胞内局在Mitochondrion outer membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Carnitine O palmitoyltransferase 1 liver isoform antibody
    • Carnitine O palmitoyltransferase I antibody
    • Carnitine O palmitoyltransferase I liver isoform antibody
    • Carnitine O-palmitoyltransferase 1 antibody
    • Carnitine O-palmitoyltransferase I antibody
    • Carnitine palmitoyltransferase 1A (liver) antibody
    • Carnitine palmitoyltransferase 1A antibody
    • Carnitine palmitoyltransferase I antibody
    • Carnitine palmitoyltransferase I liver antibody
    • CPT 1 antibody
    • CPT I antibody
    • CPT1 antibody
    • CPT1 L antibody
    • CPT1-L antibody
    • Cpt1a antibody
    • CPT1A_HUMAN antibody
    • CPTI antibody
    • CPTI-L antibody
    • L CPT1 antibody
    • liver isoform antibody
    see all

Anti-CPT1A antibody 画像

  • ab53532 antibody (0.1µg/ml) staining of CPT1A in Human Liver lysate (35µg protein in RIPA buffer).

    Predicted band size : 86 kDa
    Observed band size : 80 kDa (why is the actual band size different from the predicted?)
  • ab53532 at 4µg/ml staining CPT1A in human kidney tissue section by Immunohistochemistry (Formalin/ PFA-fixed paraffin-embedded tissue sections). The tissue underwent antigen retrieval by steam in citrate buffer pH 6.0. The AP staining procedure was successfully used.

Anti-CPT1A antibody (ab53532) 使用論文

This product has been referenced in:
  • Samudio I  et al. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction. J Clin Invest 120:142-56 (2010). WB ; Human . Read more (PubMed: 20038799) »

See 1 Publication for this product

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