製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CPT1A
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 447 and 584 of Human CPT1A (AAH00185).

  • ポジティブ・コントロール
    • A549, HeLa and HepG2 whole cell lysates. MDA-MB157 xenograft.

法規制情報

アプリケーション

Our Abpromise guarantee covers the use of ab102679 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 86 kDa.
IHC-P 1/100 - 1/500. Suggested antigen retrieval using heat mediated 10mM Citrate buffer or Tris-EDTA buffer (pH 8.0).

ターゲット情報

  • 組織特異性
    Strong expression in kidney and heart, and lower in liver and skeletal muscle.
  • パスウェイ
    Lipid metabolism; fatty acid beta-oxidation.
  • 関連疾患
    Defects in CPT1A are the cause of carnitine palmitoyltransferase 1A deficiency (CPT1AD) [MIM:255120]; also known as CPT-I deficiency or CPT1A deficiency. CPT1AD is a rare autosomal recessive metabolic disorder of long-chain fatty acid oxidation characterized by severe episodes of hypoketotic hypoglycemia usually occurring after fasting or illness. Onset is in infancy or early childhood.
  • 配列類似性
    Belongs to the carnitine/choline acetyltransferase family.
  • 細胞内局在
    Mitochondrion outer membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Carnitine O palmitoyltransferase 1 liver isoform antibody
    • Carnitine O palmitoyltransferase I antibody
    • Carnitine O palmitoyltransferase I liver isoform antibody
    • Carnitine O-palmitoyltransferase 1 antibody
    • Carnitine O-palmitoyltransferase I antibody
    • Carnitine palmitoyltransferase 1A (liver) antibody
    • Carnitine palmitoyltransferase 1A antibody
    • Carnitine palmitoyltransferase I antibody
    • Carnitine palmitoyltransferase I liver antibody
    • CPT 1 antibody
    • CPT I antibody
    • CPT1 antibody
    • CPT1 L antibody
    • CPT1-L antibody
    • Cpt1a antibody
    • CPT1A_HUMAN antibody
    • CPTI antibody
    • CPTI-L antibody
    • L CPT1 antibody
    • liver isoform antibody
    see all

画像

  • Anti-CPT1A antibody (ab102679) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 86 kDa
  • ab102679 at 1/250 dilution, staining CPT1A in a paraffin-embedded MDA-MB157 xenograft.

参考文献

ab102679 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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