製品の概要

  • 製品名Anti-CPN1 antibody [EPR6229]
    CPN1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR6229] to CPN1
  • アプリケーション適用あり: WB, ICC/IFmore details
    適用なし: Flow Cyt,IHC-P or IP
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human CPN1.

  • ポジティブ・コントロール
    • Human plasma, HepG2 and Human fetal liver lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名EPR6229
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab124874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 55, 48, 27 kDa (predicted molecular weight: 52 kDa). Note: The 48-kDa form is generated by proteolytic cleavage at the C-terminus. This subunit is cleaved into a peptide
ICC/IF 1/100 - 1/250.
  • 追加情報Is unsuitable for Flow Cyt,IHC-P or IP.
  • ターゲット情報

    • 機能Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
    • 組織特異性Synthesized in the liver and secreted in plasma.
    • 関連疾患Defects in CPN1 are the cause of carboxypeptidase N deficiency (CPND) [MIM:212070]. Patients affected present some combination of angioedema or chronic urticaria, as well as hay fever or astma, and have also slightly depressed serum carboxy peptidase N, suggestive of autosomal recessive inheritance of this disorder.
    • 配列類似性Belongs to the peptidase M14 family.
    • 細胞内局在Secreted > extracellular space.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ACBP antibody
      • Anaphylatoxin inactivator antibody
      • Arginine carboxypeptidase antibody
      • Carboxypeptidase N catalytic chain antibody
      • Carboxypeptidase N polypeptide 1 50 kD antibody
      • Carboxypeptidase N polypeptide 1 antibody
      • Carboxypeptidase N small subunit antibody
      • CBPN_HUMAN antibody
      • CPN antibody
      • CPN1 antibody
      • Kininase 1 antibody
      • Kininase-1 antibody
      • Kininase1 antibody
      • Lysine carboxypeptidase antibody
      • Plasma carboxypeptidase B antibody
      • SCPN antibody
      • Serum carboxypeptidase N antibody
      see all

    Anti-CPN1 antibody [EPR6229] 画像

    • All lanes : Anti-CPN1 antibody [EPR6229] (ab124874) at 1/1000 dilution

      Lane 1 : Human plasma lysate
      Lane 2 : HepG2 lysate
      Lane 3 : Human fetal liver lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 52 kDa
      Additional bands at : 27 kDa (possible cleavage fragment),48 kDa (possible cleavage fragment).

    Anti-CPN1 antibody [EPR6229] (ab124874) 使用論文

    ab124874 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab124874.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"