Anti-COX1 / Cyclooxygenase 1 抗体 (ab2338)

製品の概要

  • 製品名Anti-COX1 / Cyclooxygenase 1 antibody
    COX1 / Cyclooxygenase 1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to COX1 / Cyclooxygenase 1
  • 特異性This antibody is expected to recognise both human isoforms of this protein.
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide: QDDGPAVERPSTEL, corresponding to C terminal amino acids 586-599 of Human COX1/ Cyclooxygenase 1.

  • 特記事項Principal Names – PTGS1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); COX1; PHS 1; PTGHS; PGG/HS; PGHS-1; prostaglandin G/H synthase and cyclooxygenase; COX3; PCOX1 Official Gene Symbol - PTGS1 GenBank Accession Number – NP_000953; NP_542158 LocusLink ID - 5742 Gene Ontology terms - Lipid metabolism; physiological processes; prostaglandin-endoperoxide synthase

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab2338 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Can be blocked with Human COX1 / Cyclooxygenase 1 peptide (ab22901).
ELISA 1/32000.
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

ターゲット情報

  • 機能May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
  • パスウェイLipid metabolism; prostaglandin biosynthesis.
  • 配列類似性Belongs to the prostaglandin G/H synthase family.
    Contains 1 EGF-like domain.
  • 細胞内局在Microsome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • COX 1 antibody
    • COX 3 antibody
    • COX-1 antibody
    • COX1 antibody
    • Cox3 antibody
    • Cyclooxygenase 1 antibody
    • Cyclooxygenase 3, included antibody
    • Cyclooxygenase-1 antibody
    • EC 1.14.99.1 antibody
    • Partial COX1 proteins, included antibody
    • PCOX1 antibody
    • PGG/HS antibody
    • PGH synthase 1 antibody
    • PGH1_HUMAN antibody
    • PGHS-1 antibody
    • PGHS1 antibody
    • PHS 1 antibody
    • PHS1 antibody
    • Prostaglandin G/H synthase 1 antibody
    • Prostaglandin H2 synthase 1 antibody
    • Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody
    • Prostaglandin-endoperoxide synthase 1 antibody
    • PTGHS antibody
    • PTGS1 antibody
    see all

Anti-COX1 / Cyclooxygenase 1 antibody 画像

  • Ab2338 staining (1µg/ml) of HeLa lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
  • ab2338 (3.8 µg/ml) staining COX1/cyclooxygenase 1 in paraffin-embedded Human heart myocardial fibers following steamed antigen retrieval with citrate buffer (pH 6).

Anti-COX1 / Cyclooxygenase 1 antibody (ab2338) 使用論文

ab2338 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - other (Hela cells, microsome)
Loading amount 120 µg
Specification Hela cells, microsome
Gel Running Conditions Reduced Denaturing (4-12% gel)
Blocking step Milk as blocking agent for 14 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
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投稿 Apr 17 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"