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RabMAb

Anti-Cortisol Binding Globulin 抗体 [EPR4615] (ab110648)

製品の概要

  • 製品名
    Anti-Cortisol Binding Globulin antibody [EPR4615]
    Cortisol Binding Globulin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4615] to Cortisol Binding Globulin
  • アプリケーション
    適用あり: WBmore details
    適用なし: ICC,IHC-P or IP
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human Cortisol Binding Globulin.

  • ポジティブ・コントロール
    • Human fetal artery, plasma and placenta lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファー
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度
    Tissue culture supernatant
  • ポリ/モノ
    モノクローナル
  • クローン名
    EPR4615
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab110648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 60 kDa (predicted molecular weight: 45 kDa).
  • 追加情報
    Is unsuitable for ICC,IHC-P or IP.
  • ターゲット情報

    • 機能
      Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
    • 組織特異性
      Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.
    • 関連疾患
      Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency) [MIM:611489]. CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue.
    • 配列類似性
      Belongs to the serpin family.
    • 翻訳後修飾
      N-glycosylated; binds 5 oligosaccharide chains.
      Glycosylation in position Asn-260 is needed for steroid binding.
    • 細胞内局在
      Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CBG antibody
      • CBG_HUMAN antibody
      • corticosteroid binding globulin antibody
      • Corticosteroid-binding globulin antibody
      • serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6 antibody
      • Serpin A6 antibody
      • serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6 antibody
      • Serpina6 antibody
      • Transcortin antibody
      see all

    画像

    • All lanes : Anti-Cortisol Binding Globulin antibody [EPR4615] (ab110648) at 1/1000 dilution

      Lane 1 : Human fetal artery lysate
      Lane 2 : Human plasma lysate
      Lane 3 : Human placenta lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 45 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)

    プロトコール

    参考文献

    ab110648 has not yet been referenced specifically in any publications.

    レビューと Q&A

    There are currently no Customer reviews or Questions for ab110648.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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