Anti-Cortisol Binding Globulin 抗体 [EPR4615] (ab110648)

製品の概要

  • 製品名Anti-Cortisol Binding Globulin antibody [EPR4615]
    Cortisol Binding Globulin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4615] to Cortisol Binding Globulin
  • アプリケーション適用あり: WBmore details
    適用なし: ICC,IHC-P or IP
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human Cortisol Binding Globulin.

  • ポジティブ・コントロール
    • Human fetal artery, plasma and placenta lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 60 kDa (predicted molecular weight: 45 kDa).
  • 追加情報Is unsuitable for ICC,IHC-P or IP.
  • ターゲット情報

    • 機能Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
    • 組織特異性Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.
    • 関連疾患Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency) [MIM:611489]. CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue.
    • 配列類似性Belongs to the serpin family.
    • 翻訳後修飾N-glycosylated; binds 5 oligosaccharide chains.
      Glycosylation in position Asn-260 is needed for steroid binding.
    • 細胞内局在Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CBG antibody
      • CBG_HUMAN antibody
      • corticosteroid binding globulin antibody
      • Corticosteroid-binding globulin antibody
      • serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6 antibody
      • Serpin A6 antibody
      • serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 6 antibody
      • Serpina6 antibody
      • Transcortin antibody
      see all

    Anti-Cortisol Binding Globulin antibody [EPR4615] 画像

    • All lanes : Anti-Cortisol Binding Globulin antibody [EPR4615] (ab110648) at 1/1000 dilution

      Lane 1 : Human fetal artery lysate
      Lane 2 : Human plasma lysate
      Lane 3 : Human placenta lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 45 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)

    Anti-Cortisol Binding Globulin antibody [EPR4615] (ab110648) 使用論文

    ab110648 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab110648.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"